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Background The drug company Pfizer first investigated Viagra over 30 years ago in patients with lung disorder pulmonary hypertension, but soon discovered that many of the patients taking the trial drug developed an interesting side-effect. Weak erection or sildenafil Generic Viagra or tadalafil Levitra or vardenafil Penile rehabilitation - how it works Prostate removal can interfere with the function of the cavernosal erectile nerves due to their very close proximity to the prostate, as well as the arterial blood supply into the penis as some of it travels through the penis.