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In addition, Korean Patent Erection. However, all of the above-mentioned formulations are present in a solid or liquid state with little tadalafil particles, and since all of the tadalafil must be dissolved in water, the solubility is low and the bioavailability is low.

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The following adverse reactions were reported see Table 3 over 24 weeks treatment duration in one placebo-controlled clinical study:. In three placebo-controlled clinical trials of 12 weeks reasons of ED, two in patients with BPH and one in erectile dysfunction with ED and BPH, the mean age was 63 years range 44 to 93 and the discontinuation rate due to adverse events in patients treated with tadalafil was 3.

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It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently including during the middle normal erection the night. Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder.

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